Adapalene Gel 0.3% - 45 g

Adapalene Gel
  • Adapalene is bioequivalent (similar) to the brand Differin®, another product used to treat acne, they both contain adapalene which is a topical product classified as a retinoid.
  • Adapalene or retinoids work deep under the skin to help exfoliate or unclog your pores, reprogram your cells to shed, and even help prevent future breakouts.
  • Adapalene is a once-a-day acne treatment in a gel formulation, so you only have to apply it one time and the gel base is easy to spread and apply to the whole face or affected area.

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Important Information

Adapalene gel, 0.3% is a prescription medication known as a retinoid and is indicated for the topical treatment of acne vulgaris in patients 12 years and older.


Important Safety Information

  • Adapalene gel, 0.3% should not be administered to individuals who are hypersensitive to adapalene or any of the components in the vehicle gel.
  • Use of adapalene gel, 0.3% should be discontinued if hypersensitivity to any of the ingredients is noted.
  • Patients should minimize exposure to sunlight, including sunlamps, while using adapalene gel, 0.3%. If exposure cannot be avoided, sunscreen products and protective apparel should be used.
  • Weather extremes, such as wind or cold, may be irritating to patients undergoing treatment with adapalene gel, 0.3%.
  • Avoid contact of adapalene gel, 0.3% with the eyes, lips, angles of the nose and mucous membranes. Do not use adapalene gel, 0.3% on cuts, abrasions, eczematous or sunburned skin. As with other retinoids, use of waxing should be avoided on skin treated with adapalene gel, 0.3%.
  • Patients should use caution with use of adapalene gel, 0.3% in combination with potentially irritating topical products, like medicated or abrasive soaps and cleansers and products with high concentrations of astringents or alcohol. Caution should be exercised in using preparations containing sulfur, resorcinol, or salicylic acid in combinations with adapalene gel, 0.3%.
  • The most commonly reported (≥1%) adverse events in patients treated with adapalene gel, 0.3% were dry skin, skin discomfort, pruritus, desquamation, and sunburn.


For additional safety and other information, including Patient Information, please see Full Prescribing Information. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.